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Published on: February 22, 2020
Young ischaemic stroke in South Auckland: a hospital-based study
Teddy Y Wu1, Ajay Kumar, Edward H Wong
1Department of Medicine, Middlemore Hospital, Otahuhu, Auckland, New Zealand.
Insights
Young adults in South Auckland experience strokes primarily due to undetermined causes or cardioembolism. Māori and Pacific Island populations show a disproportionately higher stroke incidence.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke incidence in young adults (15-45 years) is a significant concern.
- Understanding stroke aetiology and risk factors in this demographic is crucial for targeted prevention.
Purpose of the Study:
- To analyze risk factors, incidence trends, and causes of stroke in young adults.
- To investigate stroke aetiology in a hospital-based population in South Auckland, New Zealand.
Main Methods:
- Retrospective review of ischaemic stroke patients aged 15-45 years (June 2004 - December 2009).
- Data collected included vascular risk factors, demographics, stroke severity, subtype, investigations, and outcomes.
- Discharge diagnoses utilized ICD 10 codes for ischaemic stroke.
Main Results:
- 131 patients identified (4.6% of all stroke discharges).
- Over half of strokes were of undetermined cause (Trial of Org 10172 in Acute Stroke Treatment [TOAST] criteria), mainly due to incomplete investigation.
- Cardioembolism (16%) was the second most common cause, followed by small vessel disease (12.2%).
- Most common risk factors: hyperlipidaemia (45.8%), hypertension (42.7%), smoking (42.7%), obesity (36.6%).
- Māori and Pacific Island people had at least double the stroke rate of other ethnicities.
- In-hospital fatality rate was 3.1%; 86% of survivors were independent.
Conclusions:
- Strokes of undetermined aetiology and cardioembolism are the most frequent causes in young adults in South Auckland.
- Māori and Pacific Island populations exhibit a higher stroke rate, highlighting health disparities.
Background And Purpose:
To analyse the risk factors, trends in incidence and aetiology of stroke in young adults in a hospital-based population in South Auckland, New Zealand.
Method:
A retrospective review of patients aged 15 years to 45 years with a discharge diagnosis of ischaemic stroke (ICD 10 Codes I63 - I65, G46, I672, I675-I679, I694- I694) from June 1 2004 to December 31, 2009. Vascular risk factors, demographic factors, stroke severity, stroke subtype, results of investigations and stroke outcome were determined from review of the hospital record (paper copy and electronic record).
Results:
A total of 131 patients were identified, representing 4.6% of all stroke discharges. Over one-half of the patients were of "underdetermined cause" (Trial of Org 10172 in Acute Stroke Treatment [TOAST] criteria), (1) mainly due to incomplete investigation. Cardioembolism (16%) was the second most common cause of stroke, followed by small vessel disease and stroke of other determined aetiology (both 12.2%). Confirmed large vessel atherosclerosis (6.1%) was the least common cause of stroke in this study population. The most common risk factors were hyperlipidaemia (45.8%), hypertension (42.7%), current tobacco smoking (42.7%) and obesity (36.6%). The indigenous Maori and Pacific Island people had a higher rate of stroke, at least double of other ethnicities. The in-hospital fatality rate was 3.1%. All surviving patients were discharged home. Eighty-six percent of the survivors were independent.
Conclusions:
Our study demonstrates strokes of undetermined aetiology and cardioembolism were the most common cause of stroke in young people in South Auckland, and that Māori and Pacific Island people have a higher rate of stroke.
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