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Related Experiment Video

Updated: May 16, 2026

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

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Published on: November 28, 2025

SUNCT and SUNA: Recognition and Treatment.

Juan A Pareja¹, Mónica Alvarez, Teresa Montojo

¹Department of Neurology, University Hospital Quirón Madrid, Madrid, Spain, japareja@fhalcorcon.es.

Current Treatment Options in Neurology

|December 18, 2012

Summary

Management for SUNCT and SUNA headaches remains challenging, with no definitive cure. Lamotrigine and gabapentin show promise for prevention, while intravenous lidocaine may help during severe attacks.

Area of Science:

Neurology
Headache Medicine

Background:

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) present significant management challenges.
Current therapeutic options offer limited efficacy, with no universally effective treatments available.

Purpose of the Study:

To review the current therapeutic landscape for SUNCT and SUNA.
To identify potentially effective pharmacologic, interventional, and invasive treatment strategies.

Main Methods:

Review of open-label communications and case reports on various treatment modalities.
Analysis of pharmacologic preventive agents, abortive treatments, and interventional procedures.

Main Results:

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Preventive medications like lamotrigine (for SUNCT) and gabapentin (for SUNA) show potential.
Intravenous lidocaine may offer temporary relief during severe attacks.
Interventional procedures including nerve blocks and deep brain stimulation show preliminary promise but require further investigation.

Conclusions:

Effective management for SUNCT and SUNA remains an unmet need.
While certain medications and interventions show promise, further rigorous studies are essential to validate their efficacy and establish treatment guidelines.