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Amniotic membrane in oral and maxillofacial surgery
Marco Rainer Kesting1, Klaus-Dietrich Wolff, Christopher Philipp Nobis
1Department of Oral and Maxillofacial Surgery, Klinikum rechts der Isar, Technische Universitaet Muenchen, Ismaninger Str. 22, 81675, Munich, Germany, kesting@mkg.med.tum.de.
Oral and Maxillofacial Surgery
|December 18, 2012
Summary
Preserved human amniotic membrane (HAM) is a safe and effective biomaterial for oral and maxillofacial surgery, offering pain reduction and antimicrobial benefits. Further research is needed for novel HAM applications in wound healing.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Oral and Maxillofacial Surgery
Background:
- Human amniotic membrane (HAM) has gained prominence in ophthalmology and is now explored in other surgical fields.
- HAM offers immunological advantages, pain reduction, antimicrobial properties, and aids in re-epithelialization.
Purpose of the Study:
- To review the current and potential applications of preserved human amniotic membrane (HAM) in oral and maxillofacial surgery.
- To discuss the properties and preservation techniques of HAM.
Main Methods:
- Literature search of PubMed conducted in July 2012.
- Supplementation of search results with references from consulted papers.
Main Results:
- HAM has been utilized in oral and maxillofacial surgery since 1969 due to its beneficial properties.
- Common preservation methods include glycerol, DMSO, freeze-drying, and irradiation.
- Recent applications include orbital and temporomandibular joint surgery, with tissue engineering showing significant future potential.
Conclusions:
- Preserved HAM is a safe and adequate biomaterial for oral and maxillofacial wound healing.
- Novel HAM applications require further investigation to establish a high level of evidence.
