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Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans
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Published on: March 19, 2015

Cryptococcus gattii, no longer an accidental pathogen?

Deborah J Springer1, Sujal Phadke, Blake Billmyre

  • 1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.

Current Fungal Infection Reports
|December 18, 2012
PubMed
Summary
This summary is machine-generated.

Cryptococcus gattii is an environmental fungus causing serious infections like pneumonia and meningoencephalitis. Recent findings indicate its worldwide presence, highlighting its role as a primary pathogen.

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Last Updated: May 16, 2026

Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans
07:32

Biolistic Transformation of a Fluorescent Tagged Gene into the Opportunistic Fungal Pathogen Cryptococcus neoformans

Published on: March 19, 2015

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body
08:08

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body

Published on: January 11, 2018

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Environmental Microbiology

Background:

  • Cryptococcus gattii is an environmental fungus.
  • It causes cryptococcosis, affecting humans and animals with pneumonia and meningoencephalitis.
  • This fungus associates with trees and soil, producing infectious spores and yeast.

Purpose of the Study:

  • To summarize historical literature on Cryptococcus gattii.
  • To present recent findings supporting the worldwide distribution of C. gattii.
  • To highlight C. gattii's characteristics as a primary pathogen.

Main Methods:

  • Literature review of historical and recent publications.
  • Analysis of clinical and environmental isolation reports.
  • Synthesis of data on C. gattii's pathogenic mechanisms and ecological associations.

Main Results:

  • Cryptococcus gattii is increasingly reported in temperate climates globally.
  • The fungus demonstrates an ability to infect immunocompetent hosts.
  • C. gattii exhibits unique survival, multiplication, and host cell interaction capabilities.

Conclusions:

  • Cryptococcus gattii is a primary pathogen with a worldwide distribution.
  • Its pathogenic potential is linked to its environmental interactions and host cell dynamics.
  • Further research is warranted to understand C. gattii's evolution and global impact.