Thoracic endografting reduces morbidity and remodels the thoracic aorta in DeBakey III aneurysms

Bradley G Leshnower1, Wilson Y Szeto, Alberto Pochettino

  • 1Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.

Insights

Thoracic endovascular aortic repair (TEVAR) offers a less invasive option for chronic DeBakey type III aortic dissection aneurysms, significantly reducing operative mortality and morbidity compared to open repair. TEVAR effectively remodels the aorta and stabilizes aneurysm size.

Area of Science:

  • Cardiovascular Surgery
  • Endovascular Interventions
  • Aortic Aneurysm Treatment

Background:

  • Efficacy of endovascular treatment for chronic DeBakey type III aortic dissection (CD3) aneurysms is debated.
  • Comparison of open versus endovascular repair for CD3 aneurysms is needed.
  • Assessment of thoracic endovascular aortic repair (TEVAR) for remodeling chronically dissected thoracoabdominal aorta.

Purpose of the Study:

  • To compare outcomes between open and endovascular treatment of CD3 aneurysms.
  • To evaluate the efficacy of TEVAR in remodeling the thoracoabdominal aorta.
  • To analyze the impact of TEVAR on true and false lumen dimensions.

Main Methods:

  • Retrospective analysis of 58 patients undergoing open repair and 31 patients undergoing TEVAR for CD3 aneurysms (2005-2012).
  • Subgroup analysis of TEVAR patients into CD3a (n=12) and CD3b (n=19).
  • Measurement of aortic dimensions and calculation of lumen indices to assess remodeling.

Main Results:

  • Open repair had 10.3% operative mortality and significant rates of pulmonary, renal failure, and paraplegia.
  • TEVAR group had no operative mortality or major complications.
  • TEVAR stabilized aneurysms in 87% of patients, significantly expanding the true lumen and reducing false lumen (p < 0.001).
  • Thoracic false lumen thrombosis achieved in 100% of CD3a and 68% of CD3b patients.

Conclusions:

  • TEVAR demonstrates reduced operative morbidity and mortality compared to open repair for CD3 aneurysms.
  • TEVAR is effective in remodeling the chronically dissected thoracic aorta.
  • Abdominal false lumen patency is maintained in thoracoabdominal dissection-related aneurysms.
Abstract