Medical complication in adults with spina bifida
L Werhagen1, H Gabrielsson, N Westgren
1Division of Rehabilitation Medicine, Department of Clinical Sciences, Karolinska Institute at Danderyds Hospital, Stockholm, Sweden. lars.werhagen@ki.se
Insights
Spina bifida (SB) patients experience frequent medical issues like urinary tract infections and scoliosis. Regular medical check-ups are crucial for managing these complications in adults with SB.
Area of Science:
- Neurology
- Pediatric Medicine
- Rehabilitation Medicine
Background:
- Spina bifida (SB) is a common congenital central nervous system (CNS) malformation in children.
- Hydrocephalus (HC) affects approximately 80% of newborns with SB.
- Understanding long-term complications in adults with SB is vital for ongoing care.
Purpose of the Study:
- To analyze medical complications in adults with spina bifida.
- To correlate complications with age, injury level, AIS grade, and hydrocephalus.
- To inform follow-up examination protocols for SB patients.
Main Methods:
- A cohort study involving 127 adult SB patients from a specialized clinic.
- Data collection included neurological examinations and review of medical files.
- Analysis focused on medical complications and associated factors.
Main Results:
- 69% of patients experienced at least one medical complication.
- Urinary tract infections (46%), scoliosis (30%), and pain (28%) were most prevalent.
- Hydrocephalus was present in nearly 60% of patients.
Conclusions:
- Adults with SB face significant disability and a high incidence of medical complications.
- Common issues include urinary tract infections, scoliosis, pain, and epilepsy.
- Findings support the need for structured medical examination routines during follow-up.
Setting:
Cohort study.
Introduction:
Spina bifida (SB) is a congenital malformation affecting the central nervous system (CNS) and is one of the most prevalent CNS disorders in children. Hydrocephalus (HC) is present in 80% of newborns with SB. The aim of the present study was to analyze the medical complications and to relate the complications to age at examination, the level of injury, AIS grade and presence of HC in adults with SB.
Materials And Methods:
SB patients were recruited from the Spinalis out-patient clinic at the Karolinska University Hospital at their annual follow-up. The patients underwent a thorough general and neurological examination and background data including medical complications were retrieved from the medical files.
Results:
127 of 157 (82%) SB patients (114 with MMC and 13 SB occulta) with a mean age of 34 years were included. Half of the patients had a complete SCI and a lumbar level was most common. Nearly 60% of the patients had HC. 88 patients (69%) suffered from at least one medical complication. Urinary tract infection (UTI), scoliosis and pain were the most common complications found in 46%, 30% and 28% of the patients, respectively. Less common complications were epilepsy, pressure ulcers (PU) and spasticity.
Discussion:
SB gives a disability including motor, sensory dysfunctions and the patients suffer from a high frequency of medical complications like UTI, scoliosis, pain, and epilepsy. Data gives basis for adequate routines for medical examination at the follow-up.
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