Related Experiment Video
Updated: May 15, 2026

Intracameral Injection in Rats with Low Risk of Adverse Effects
Published on: May 31, 2024
[Prevention of post intravitreal injection endophthalmitis: is antibioprophylaxis indicated?]
I Cochereau1, J-F Korobelnik, B Bodaghi
1UMR-S 976, université Paris-Diderot, Sorbonne Paris-Cité, CHU Bichat-Fondation Rothschild, 25, rue Manin, 75019 Paris cedex 10, France. icochereau@fo-rothschild.fr
Abstract:
Endophthalmitis remains the main complication of intravitreal injections, especially because their repetition multiplicates the risks. Surgical antisepsis is required for the prevention of endophthalmitis, but the benefit/risk ratio of topical antibioprophylaxis has never been demonstrated. In contrast, the selection of resistant bacteria appears to be exponential with the wider use of topical antibioprophylaxis. It seems that more and more operators stop using anibioprophylaxis, provided that the antisepsis is surgical and that the injection is performed in accordance with the rules of good practice.
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