Anatomically reproducible assessment of volumetric bone mineral density--based on clinical computed tomography

Local distribution and quality of bone mineral density (BMD) in the proximal humerus are important for rotator cuff repair, internal fixations, and arthroplasty. The current study aimed to develop a volumetric BMD (vBMD) measurement technique that can specify the volumetric region of interest in an anatomically reproducible manner and ensures fair comparison of vBMD among intrasubjective or intersubjective measurements. Computed toed into three-dimensional (3D) polygon models. A standardized volumetric block was asmographic images of 10 intact shoulders (from six women and four men, age range 46-69 years) were reconstruct signed, and it included whole insertion areas of the supraspinatus and infraspinatus tendons on the greater tuberosity. For standardizing a bone block, a mathematical method for reproducible landmark assignment and reproducible local coordinate system was developed. After converting the polygonal standardized volumetric block into 3D tetrahedron finite element models, its vBMD was calculated. The repeatability and reproducibility standard deviations of the vBMD measurement method were found to be less than 2%. The current study developed a vBMD measurement technique that can specify the vROI in an anatomically reproducible manner and ensures fair comparison of BMD among intrasubjective or intersubjective measurements, with less than 2% reproducibility error.