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Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...

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Related Experiment Video

Updated: May 15, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Epileptic diaphragm myoclonus.

Andreas Hahn1, Bernd A Neubauer

  • 1Department of Neuropediatrics, University of Giessen, Giessen, Germany. andreas.hahn@paediat.med.uni-giessen.de

Epileptic Disorders : International Epilepsy Journal with Videotape
|December 19, 2012
PubMed
Summary
This summary is machine-generated.

Persistent hiccups in a child were linked to a rare form of epilepsy. Electrophysiological findings suggest a generalized epilepsy with diaphragm myoclonus triggered by brain activity.

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Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
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Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Published on: October 26, 2014

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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Published on: September 20, 2024

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
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Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Published on: October 26, 2014

Area of Science:

  • Neurology
  • Epileptology
  • Clinical Neurophysiology

Background:

  • Persistent singultus (hiccups) is uncommon and can stem from central nervous system disorders.
  • Epilepsy is a neurological condition characterized by recurrent seizures.
  • Diaphragmatic myoclonus refers to involuntary contractions of the diaphragm.

Observation:

  • A six-year-old girl presented with daily, persistent hiccups.
  • Polygraphic recordings captured hiccup episodes associated with specific electroencephalogram (EEG) and electromyogram (EMG) patterns.

Findings:

  • Singultus episodes were time-locked to bilateral, synchronous, double-spike-and-wave EEG discharges.
  • Diaphragm myoclonus occurred consistently with these EEG abnormalities.
  • EEG spikes preceded EMG discharges, indicating a central nervous system origin.

Implications:

  • This case represents the first documented instance of epilepsy manifesting primarily as hiccups.
  • The findings suggest a generalized epilepsy with polysynaptic impulse transmission causing diaphragmatic myoclonus.
  • This highlights the importance of considering neurological causes for persistent hiccups, especially in pediatric cases.