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Current treatment strategies: collagen vascular diseases in children

Aparna Palit1, Arun C Inamadar

  • 1Department of Dermatology, Venereology and Leprosy, Sri B. M. Patil Medical College, Hospital and Research Center, BLDE University, Bijapur, Karnataka, India.

Indian Journal of Dermatology
|December 19, 2012
PubMed

Insights

Pediatric collagen vascular diseases like lupus and scleroderma require diverse treatments. Newer options such as stem cell transplant and biologics offer hope for difficult cases.

Area of Science:

  • Pediatric rheumatology
  • Autoimmune diseases
  • Collagen vascular diseases

Background:

  • Common pediatric collagen vascular diseases include discoid lupus erythematosus, systemic lupus erythematosus, neonatal lupus erythematosus, juvenile dermatomyositis, and childhood scleroderma.
  • These conditions pose significant clinical challenges for healthcare providers.
  • Understanding their varied presentations and treatment needs is crucial.

Purpose of the Study:

  • To review common collagen vascular diseases in children.
  • To discuss conventional and advanced treatment modalities.
  • To highlight recent therapeutic options for refractory pediatric cases.

Main Methods:

  • Literature review of pediatric collagen vascular diseases.
  • Discussion of established and novel treatment strategies.
  • Focus on therapeutic options for challenging pediatric presentations.

Main Results:

  • Identified key pediatric collagen vascular diseases and their clinical relevance.
  • Outlined a spectrum of treatment approaches, from routine to advanced.
  • Emphasized the availability of newer therapies for severe or resistant cases.

Conclusions:

  • Effective management of pediatric collagen vascular diseases requires a comprehensive approach.
  • Advanced therapies like autologous stem cell transplant and biologics are vital for difficult-to-treat conditions.
  • Intravenous immunoglobulin and narrow-band ultraviolet B represent emerging options in pediatric rheumatology.

Keywords:
Childrencollagen vascular diseaseslupus erythematosus

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