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Published on: October 13, 2015
Omics strategies for revealing Yersinia pestis virulence
Ruifu Yang1, Zongmin Du, Yanping Han
1Beijing Institute of Microbiology and Epidemiology Beijing, China. ruifuyang@gmail.com
Abstract:
Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of Yersinia pestis through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into Y. pestis pathogenesis.
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