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Functional abdominal pain in childhood: background studies and recent research trends
Rona L Levy1, Miranda A L van Tilburg
1University of Washington, Seattle, WA, USA. rlevy@uw.edu
Insights
This review covers recent pediatric functional abdominal pain research, including genetics and treatment. Findings offer a framework for understanding how pain develops and persists in children.
Area of Science:
- Pediatric Gastroenterology
- Pain Medicine
- Genetics
Background:
- Functional abdominal pain is common in children, with significant healthcare costs.
- Understanding its etiology and mechanisms is crucial for effective management.
- Recent research has explored various facets, from genetics to treatment.
Purpose of the Study:
- To review major research trends in pediatric functional abdominal pain over the past five years.
- To summarize key findings from the authors' research program in this area.
- To provide a framework for understanding pain development and maintenance in children.
Main Methods:
- Literature review of studies published in the last five years.
- Inclusion of findings from the authors' specific research group.
- Discussion of familial patterns, genetics, traits, and pain mechanisms.
Main Results:
- Prevalence, cost, and longitudinal outcomes of pediatric functional abdominal pain have been investigated.
- Overlap with other disorders and the underlying etiology and mechanisms are key research areas.
- Treatment studies show varied approaches and outcomes.
Conclusions:
- Pediatric functional abdominal pain research has advanced significantly in understanding its complex nature.
- Familial, genetic, and mechanistic factors play a role in pain development and persistence.
- Recommendations for clinical practice and future research are provided.
Abstract:
The present review summarizes many of the major research trends investigated in the past five years regarding pediatric functional abdominal pain, and also summarizes the primary related findings from the authors' research program. Specific areas discussed based on work within the authors' group include familial illness patterns, genetics, traits, and mechanisms or processes related to abdominal pain. Topics covered from research published in the past five years include prevalence and cost, longitudinal follow-up, overlap with other disorders, etiology and mechanisms behind functional abdominal pain and treatment studies. It is hoped that findings from this work in abdominal pain will be interpreted as a framework for understanding the processes by which other pain phenomena and, more broadly, reactions to any physical state, can be developed and maintained in children. The present article concludes with recommendations for clinical practice and research.
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