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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...

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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
05:06

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

[Diabetic neuropathy].

Monika Lechleitner1, Heidemarie Abrahamian, Mario Francesconi

  • 1Interne Abteilung, Landeskrankenhaus Hochzirl, Hochzirl, Österreich. monika.lechleitner@tilak.at

Wiener Klinische Wochenschrift
|December 20, 2012
PubMed
Summary
This summary is machine-generated.

These guidelines detail the diagnosis and treatment of diabetic neuropathy, a common complication. They cover clinical symptoms, diagnostic methods, and therapeutic strategies, focusing on pain management in sensorimotor neuropathy.

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Last Updated: May 15, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
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An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models
10:27

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Published on: October 20, 2017

Area of Science:

  • Neurology
  • Endocrinology

Context:

  • Diabetic neuropathy is a significant late complication of diabetes mellitus.
  • It encompasses various forms including mononeuropathies, polyneuropathies, plexopathies, radiculopathies, and autonomic neuropathy.

Purpose:

  • To provide comprehensive guidelines for the diagnosis and treatment of diabetic neuropathy.
  • To summarize characteristic clinical symptoms and diagnostic assessment techniques.
  • To offer recommendations for therapeutic management, emphasizing pain control in sensorimotor neuropathy.

Summary:

  • The position statement outlines diagnostic criteria and therapeutic approaches for diabetic neuropathy.
  • It details clinical manifestations and diagnostic assessment tools.
  • Management strategies, particularly for pain in sensorimotor neuropathy, are recommended.

Impact:

  • Improved diagnostic accuracy for diabetic neuropathy.
  • Standardized treatment protocols for better patient outcomes.
  • Enhanced management of pain associated with sensorimotor diabetic neuropathy.