[The changes in the brain's electrical activity in children with cerebral palsy during the complex rehabilitation]

Area of Science:

• Neurology
• Pediatrics
• Rehabilitation Medicine

Background:

• Spastic diplegia cerebral palsy (CP) is a common motor disorder in children.
• Effective rehabilitation strategies are crucial for improving functional outcomes in children with CP.

Purpose of the Study:

• To evaluate the efficacy of microcurrent therapy (MENS) and cortexin in children with spastic diplegia cerebral palsy.
• To compare the effects of MENS alone, MENS with cortexin, and standard therapy on cognitive and motor functions.

Main Methods:

• 105 children (3-7 years) with spastic diplegia CP were divided into three groups.
• Group I received MENS plus standard therapy; Group II received MENS plus cortexin and standard therapy; Group III received standard therapy (massage, gymnastics).
• MENS involved 15 sessions per course; Cortexin was administered intramuscularly (10 mg/day for 10 days).

Main Results:

• 66% of children in the MENS plus cortexin group showed improved cognitive and motor skills, compared to 50% in the MENS group and 16% in the standard therapy group.
• Brain electrical activity improvements were observed in 82% of children receiving MENS plus cortexin, 75% receiving MENS, and 64% receiving standard therapy.
• The combination of MENS and cortexin yielded the most significant positive changes.

Conclusions:

• Microcurrent therapy, particularly when combined with cortexin, demonstrates significant therapeutic benefits for children with spastic diplegia cerebral palsy.
• This combined approach enhances cognitive functions, motor skills, and brain electrical activity more effectively than standard therapy alone.
• Further research into optimizing MENS and pharmacological interventions for pediatric CP is warranted.