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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

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Related Experiment Video

Updated: May 15, 2026

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

Development of new technologies for stem cell research.

Xibo Ma¹, Qian Zhang, Xin Yang

¹Intelligent Medical Research Center, State Key Laboratory of Management and Control for Complex Systems, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.

Journal of Biomedicine & Biotechnology

|December 20, 2012

Summary

Recent advancements in stem cell research focus on improved isolation, culture, and observation techniques. Molecular imaging aids in understanding disease mechanisms and evaluating stem cell therapies, highlighting future applications.

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Micro-scale Engineering for Cell Biology

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Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research

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Published on: June 10, 2016

Area of Science:

Regenerative Medicine
Biotechnology
Medical Imaging

Background:

Stem cell research, initiated in the 1960s, encompasses various types like embryonic, neural, hematopoietic, and mesenchymal stem cells.
Stem cells are increasingly utilized in disease treatment, exemplified by bone marrow transplantation.
Significant progress in stem cell isolation, culture, and molecular imaging technologies has occurred recently.

Purpose of the Study:

To review typical isolation, culture, and observation techniques for stem cells.
To introduce recent advancements in stem cell research and technology.
To discuss current challenges and future applications of new technologies in stem cell research.

Main Methods:

Focus on typical isolation and culture techniques for stem cells.
Review of molecular imaging technologies (optical, PET, SPECT, CT) applied to stem cell research.
Analysis of recent technological developments in stem cell research.

Main Results:

Isolation, culture, and observation technologies for stem cells have been widely developed.
Molecular imaging technologies have advanced rapidly and are applied to stem cell research.
These technologies aid in studying disease mechanisms and evaluating stem cell treatments.

Conclusions:

Recent technological advancements facilitate deeper understanding and application of stem cells.
Challenges in current stem cell technologies need addressing for future progress.
Future applications of new technologies promise significant impact in regenerative medicine and disease treatment.