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Fetal brain disruption sequence: a milder variant

C G Bönnemann1, P Meinecke

  • 1Altonaer Kinderkrankenhaus, Hamburg, Federal Republic of Germany.

We report on a female infant with severe microcephaly, scalp rugae, overlapping sutures, and telancephalic damage with relatively satisfactory early motor development. This case represents a milder form of the 'fetal brain disruption sequence', which is thought to be the result of an exogenous insult to the developing brain during the second half of gestation.

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