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1Department of Public Policy and Political Science, Duke Institute for Brain Sciences, Duke Institute for Genome Sciences and Policy, Duke University, Durham, NC 90239, USA.
The Behavioral and Brain Sciences
|December 20, 2012
Summary
This commentary discusses behavior genetics, addressing candidate gene association studies and twin study methodology. It reflects on the conception of human nature fostered by these research approaches.
Area of Science:
- Behavior genetics
- Human nature studies
Background:
- The article responds to commentaries on a target publication.
- It addresses specific methodologies within behavior genetics.
Purpose of the Study:
- To discuss candidate gene association studies and gene-environment interactions.
- To critically evaluate the twin study methodology.
- To reflect on the broader implications for understanding human nature.
Main Methods:
- Commentary and response format.
- Critical analysis of existing methodologies in behavior genetics.
- Discussion of twin study defenses.
Main Results:
- Identifies areas of agreement and disagreement with commentaries.
- Highlights issues with candidate gene association studies, including gene × environment interactions.
- Presents a detailed critique of the twin study methodology.
Conclusions:
- Suggests limitations in current behavior genetics research methods.
- Proposes re-evaluation of the twin study methodology's influence on understanding human nature.
