Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Stages of Infection01:26

Stages of Infection

Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pediatric Humeral Tuberosity Fractures: Presentation, Management, and Early Outcomes.

Journal of the Pediatric Orthopaedic Society of North America·2026
Same author

Epidemiology of early-onset and late-onset invasive infections in Australian neonates and infants: a retrospective multicentre study.

BMJ public health·2025
Same author

Nerve Recovery in Pediatric Supracondylar Humeral Fractures: Assessing the Impact of Time to Surgery.

The Journal of bone and joint surgery. American volume·2025
Same author

Respiratory virus detections in children presenting to an Australian paediatric referral hospital pre-COVID-19 pandemic, January 2014 to December 2019.

PloS one·2025
Same author

Risk Model-Guided Clinical Decision Support for Suicide Screening: A Randomized Clinical Trial.

JAMA network open·2025
Same author

Antimicrobial Resistance in Staphylococcus aureus and Enterococcus spp. Isolates From Bloodstream Infections in Australian Children, 2013-2021.

Journal of the Pediatric Infectious Diseases Society·2024
Same journal

Effectiveness of Therapeutic and Educational Interventions for Childhood Separation Anxiety: A Scoping Review.

Journal of paediatrics and child health·2026
Same journal

Impact of Access to Pasteurised Donor Human Milk on Rates of Necrotising Enterocolitis in Neonatal Units in Australia: A Cohort Study.

Journal of paediatrics and child health·2026
Same journal

Prescribing Cascade in Children With Chronic Complex Diseases: An Argument for De-Escalation and Medication Review, a Case Report.

Journal of paediatrics and child health·2026
Same journal

Post-COVID-19 Autonomic Dysfunction in an Adolescent: Ogilvie Syndrome With Acute Urinary Retention.

Journal of paediatrics and child health·2026
Same journal

Serial Ultrasonography-Guided Management of Primary Sternal Osteomyelitis With Abscess Formation in a Child: A Case Report.

Journal of paediatrics and child health·2026
Same journal

"Raccoon Eyes": A Rare Presentation of Paediatric Scrub Typhus.

Journal of paediatrics and child health·2026
See all related articles

Related Experiment Video

Updated: May 15, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Recurrent fevers.

David Isaacs1, Alison Kesson, David Lester-Smith

  • 1The Children's Hospital at Westmead, Westmead, New South Wales, Australia. davidi@chw.edu.au

Journal of Paediatrics and Child Health
|December 21, 2012
PubMed
Summary
This summary is machine-generated.

Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is a rare genetic disorder. This case highlights TRAPS in an 11-year-old girl with recurrent fevers, urticaria, and joint pain, confirmed by genetic testing.

Related Experiment Videos

Last Updated: May 15, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Area of Science:

  • Genetics
  • Immunology
  • Rheumatology

Background:

  • Periodic fever syndromes are a group of rare autoinflammatory disorders.
  • Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is one such condition, characterized by recurrent fevers and systemic inflammation.

Observation:

  • An 11-year-old girl presented with recurrent episodes of prolonged fever (7-10 days), headache, and neck stiffness.
  • She had a history of recurrent urticaria preceding fevers and vague joint pains.
  • Elevated C-reactive protein (41 g/L) indicated moderate systemic inflammation.

Findings:

  • The clinical presentation, including prolonged fevers, headache, arthralgia, and urticaria, suggested a periodic fever syndrome.
  • Genetic testing confirmed a mutation consistent with tumor necrosis factor receptor-associated periodic syndrome (TRAPS).

Implications:

  • This case underscores the importance of considering TRAPS in pediatric patients with recurrent fevers and associated symptoms.
  • Early diagnosis through genetic testing is crucial for appropriate management and improved patient outcomes.
  • Understanding the genetic basis of TRAPS aids in differentiating it from other autoinflammatory and rheumatologic conditions.