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[Studies on ECMO. (III)--Study on pumpless A-V ECMO].

Y Tanaka1

  • 1Department of Anesthesiology, Fukushima Medical College.

Masui. the Japanese Journal of Anesthesiology
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

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This study shows that an outside flow type silicon hollow fiber membrane oxygenator is effective for CO2 removal during pumpless arterio-venous extracorporeal membrane oxygenation (ECMO). This technology is considered clinically useful for long-term respiratory support.

Area of Science:

  • Biomedical Engineering
  • Respiratory Physiology
  • Medical Devices

Context:

  • Silicon hollow fiber membrane oxygenators are used for extracorporeal membrane oxygenation (ECMO).
  • Traditional inside flow designs face limitations.
  • Outside flow designs offer potential advantages in pressure drop.

Purpose:

  • To evaluate the performance of an outside flow type silicon hollow fiber membrane oxygenator.
  • To assess the efficacy of pumpless arterio-venous ECMO (A-V ECMO) using this device.
  • To investigate hemodynamic effects and gas exchange during A-V ECMO.

Summary:

  • A pilot study demonstrated a pressure drop of 50 mmHg at 400 ml/min blood flow and a CO2 transfer rate of 22.3 ml/min.
  • Pumpless A-V ECMO was performed in 8 dogs under mechanical hypoventilation.

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  • Hemodynamics remained stable (blood flow at 15% cardiac output), with significant recovery of PaO2 and PaCO2.

    • Impact:

    • Presents a novel outside flow configuration for membrane oxygenators.
    • Demonstrates the clinical utility of pumpless A-V ECMO for CO2 removal.
    • Highlights the potential for improved long-term ECMO therapy.