Related Experiment Video
Updated: Sep 15, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Can radiologic features of community-acquired pneumonia presume etiologic agents?]
Abstract:
During a one-year and nine months (from June 1987 to February 1989) survey of community-acquired pneumonia, we investigated in 130 patients if radiologic features presume etiologic agents. Incidences of etiologic agents are 21 (16%) pneumococcus, 18 (14%) mycoplasma, 14 (11%) tuberculosis, 12 (9%) hemophilus, and 54 (42%) unknown agents, respectively. In correlates of radiologic features and etiologic agents, alveolar shadows spreading bilateral lungs presume tuberculosis and pneumococcal pneumonia. Lobar distributing alveolar shadows presume pneumococcal, mycoplasmal tuberculous diseases and other agents, equally. Segmentally distributing shadows presume pneumococcal and mycoplasma pneumonia. Radiologic subgrouping features of alveolar shadows composed of acinar, lobular, and lobar shadows did not presume specific agents. Centrilobular (peribronchiolar) shadows suspect hemophilus infections. Pleural fluid accumulations suspect tuberculosis and anaerobic infections and cavitary shadows, tuberculosis, respectively. Radiologic features can presume etiologic agents.
Insights
Radiologic features can help identify causes of community-acquired pneumonia. Specific patterns like bilateral alveolar shadows suggest tuberculosis or pneumococcal pneumonia, aiding in diagnosis.
Area of Science:
- Pulmonology
- Radiology
- Infectious Diseases
Background:
- Community-acquired pneumonia (CAP) diagnosis often relies on identifying the causative agent.
- Radiographic findings are crucial in evaluating pneumonia but their correlation with specific etiologies requires further investigation.
Purpose of the Study:
- To investigate the correlation between radiologic features and specific etiologic agents in community-acquired pneumonia.
- To determine if characteristic radiographic patterns can predict the causative pathogens of CAP.
Main Methods:
- A survey of 130 patients with community-acquired pneumonia was conducted over 21 months (June 1987-February 1989).
- Patients' radiologic features were analyzed and correlated with identified etiologic agents.
- Etiologic agents included Streptococcus pneumoniae, Mycoplasma pneumoniae, Mycobacterium tuberculosis, and Haemophilus influenzae, with a significant proportion of unknown agents.
Main Results:
- Bilateral alveolar shadows were associated with tuberculosis and pneumococcal pneumonia.
- Lobar and segmental shadow distributions showed varying correlations with pneumococcal, mycoplasmal, and tuberculous etiologies.
- Centrilobular (peribronchiolar) shadows suggested Haemophilus infections, while pleural effusions and cavitary shadows indicated tuberculosis or anaerobic infections.
Conclusions:
- Radiologic features can provide valuable clues for presuming specific etiologic agents in community-acquired pneumonia.
- While some patterns are suggestive, a significant percentage of CAP cases remain with unknown etiologies based on this study.
- Further research may refine the diagnostic utility of imaging in guiding pneumonia treatment.
More Related Videos
07:27Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa
Published on: July 12, 2018
08:05Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia II: Pathophysiology
Pneumonia III: Complications and Assessment
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Atypical Pneumonia
Pneumonia I: Introduction