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Related Experiment Videos

[Brain tumors in infants].

J Issakainen1, U Willi, E Boltshauser

  • 1Universitätskinderklinik Zürich.

Klinische Padiatrie
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Pediatric brain tumors in infants present unique challenges, with seizures being a common initial symptom. Early diagnosis and surgical intervention are crucial for improving outcomes in these young patients.

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Area of Science:

  • Pediatric Neurosurgery
  • Pediatric Oncology
  • Neurology

Context:

  • Retrospective analysis of 15 infants treated for brain tumors at Children's University Hospital of Zürich between 1975 and 1987.
  • Investigated the clinical presentation, localization, and surgical management of infant brain tumors.
  • 3 cases presented with initial symptoms at birth, highlighting congenital onset possibilities.

Purpose:

  • To describe the clinical characteristics and outcomes of brain tumors in a cohort of infants.
  • To evaluate the efficacy of surgical interventions for pediatric brain tumors.
  • To identify common presenting symptoms and tumor locations in this age group.

Summary:

  • Epileptic convulsions were the most frequent initial manifestation (40%).

Related Experiment Videos

  • Symptoms of increased intracranial pressure were observed in one-third of cases.
  • Tumors were predominantly supratentorial (73%), with fewer in the cerebellum and brainstem.
  • Surgical exploration was performed in 13 children with no perioperative mortality; radical or subtotal tumor excision was achieved in all operated cases.

    • Impact:

    • Highlights the diagnostic challenges, as clinical symptoms and EEG often failed to localize tumors.
    • Demonstrates the feasibility and safety of surgical management for infant brain tumors.
    • Provides insights into the natural history and management strategies for pediatric brain tumors.