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Updated: May 15, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve surgery for marantic endocarditis and multiple cerebral embolisation.
Sherif Moustafa1, David J Patton, Yvonne Balon
1Adult Congenital Heart Disease Clinic, Peter Lougheed Hospital, Division of Cardiovascular Diseases, University of Calgary, Canada.
Heart, Lung & Circulation
|December 21, 2012
Summary
Antiphospholipid syndrome (APS) can cause heart valve problems and stroke. This case study shows successful mitral valve replacement in an APS patient with multiple cerebral infarcts and valve vegetations.
Area of Science:
- Cardiology
- Rheumatology
- Vascular Medicine
Background:
- Antiphospholipid syndrome (APS) is associated with a higher risk of thrombo-embolic events.
- Valvular heart disease is a recognized, though less common, manifestation of APS.
Observation:
- A patient with APS presented with multiple cerebral infarcts.
- Echocardiography revealed verrucous vegetations on the mitral valve, consistent with marantic endocarditis.
Findings:
- The patient underwent successful mitral valve replacement surgery.
- Short-term follow-up demonstrated excellent clinical and echocardiographic outcomes.
Implications:
- This case highlights the importance of considering valvular pathology in APS patients with neurological events.
- Early diagnosis and intervention, such as valve replacement, can lead to favorable outcomes in APS-related cardiac complications.
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