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Linezolid surveillance results for the United States: LEADER surveillance program 2011
Robert K Flamm1, Rodrigo E Mendes, James E Ross
1JMI Laboratories, North Liberty, Iowa, USA. Robert-flamm@jmilabs.com
Abstract:
The LEADER surveillance program monitors the in vitro activity of linezolid and comparator agents against Gram-positive bacteria in the United States. In its eighth consecutive year (2011), a total of 60 medical centers from the United States, including seven medical centers specializing in children's health care contributed a total of 7,303 Gram-positive pathogens. The MIC(90) value for Staphylococcus aureus was 2 μg/ml, and for coagulase-negative staphylococci, enterococci, Streptococcus pneumoniae, β-hemolytic streptococci, and viridans group streptococci, the MIC(90) was 1 μg/ml. The "all organism" linezolid-resistant and nonsusceptible rate was only 0.19%.
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