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Updated: May 15, 2026
10:45
A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
Silicosis in India: past and present.
1Department of Pulmonary Medicine, Postgraduate Institute of Medical, Education & Research, Chandigarh, India. dr.skjindal@gmail.com
Current Opinion in Pulmonary Medicine
|December 21, 2012
Summary
Silicosis is a widespread occupational lung disease in India, affecting millions of workers exposed to silica dust. This review highlights its clinical impact and the urgent need for national preventive measures.
Area of Science:
- Occupational Medicine
- Pulmonology
- Public Health
Background:
- Silicosis is a significant occupational hazard in India.
- Millions of workers face exposure to silica and quartz dust in mining and construction.
Purpose of the Study:
- To review the burden and clinical manifestations of silicosis in India.
- To highlight the national human rights concern associated with this occupational disorder.
Main Methods:
- Literature review of reported cases and estimates from India.
- Analysis of clinical manifestations and complications.
- Examination of national-level recommendations and interventions.
Main Results:
- Over 3 million workers are exposed to silica dust, with 8.5 million more in construction.
- Lung function assessments reveal restrictive and obstructive patterns.
- Common complications include tuberculosis, silico-mycosis, lung cancer, and connective tissue disorders.
Conclusions:
- Silicosis is prevalent across India, especially in Central and Western states.
- It is a major contributor to respiratory morbidity.
- The National Human Rights Commission is addressing silicosis as a human rights issue.
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