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Updated: May 15, 2026
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Capture and Release of Viable Circulating Tumor Cells from Blood
Published on: October 28, 2016
Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures
Shuang Hou1, Haichao Zhao, Libo Zhao
1Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095-1770, USA.
Advanced Materials (Deerfield Beach, Fla.)
|December 21, 2012
Abstract:
A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.
