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Updated: May 15, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Children's Oncology Group's 2013 blueprint for research: cancer control and supportive care
Lillian Sung1, Theo Zaoutis, Nicole J Ullrich
1Department of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. lillian.sung@sickkids.ca
Abstract:
In cancer control research, the objective is to reduce overall morbidity and mortality by decreasing acute and delayed treatment-related toxicities in all children with cancer. To date, the Children's Oncology Group (COG) has focused on infection, neurocognition, quality of life (QoL), and nutrition/antiemetics. COG is conducting randomized controlled trials (RCTs) to determine prophylaxis strategies that will reduce infections in high-risk populations. Two RCTs are determining if modafinil or computerized cognitive training improve cognitive functioning in pediatric brain tumor patients. QoL is being assessed in acute leukemia patients. Improved supportive care outcomes will only occur when the most effective interventions are established.
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