Challenges in transcatheter aortic valve implantation
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Updated: May 15, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Stefan Toggweiler1, John G Webb
1St. Paul's Hospital, University of British Columbia, Vancouver, Canada. stefan.Toggweiler@luks.ch
Abstract:
Although safety and efficacy of TAVI was improved with next-generation equipment, experience, and careful patient selection, some worrisome complications associated with the procedure remain. Current hot topics in transcatheter aortic valve implantation include patient selection, valve sizing, paravalvular regurgitation, cerebrovascular accidents, vascular complications and need for a permanent pacemaker. In this article we review the pathophysiology, avoidance and treatment options for these complications.