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Updated: May 15, 2026

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Published on: November 19, 2008
Anatomical patterns and correlated MRI findings of non-perinatal hypoxic-ischaemic encephalopathy
M L White1, Y Zhang, J T Helvey
1Department of Radiology, University of Nebraska Medical Center, Omaha, NE, USA. mattewwhite@unmc.edu
Abstract:
Non-perinatal hypoxic-ischaemic encephalopathy (HIE) has varying anatomical patterns dependent on the type of insult, the degree and duration of cerebral hypoxia, or presence and degree of hypoperfusion. Profound insults can affect the entire cerebral cortex or just the perirolandic cortex, the cerebellum and the deep grey matter structures. Less severe insults may affect only the watershed regions. The objective of this article is to review the anatomical patterns of non-perinatal HIEs by MRI.
