Techniques for respiration-induced artifacts reductions in thoracic PET/CT
1Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.
Abstract:
The advent of positron emission tomography/computed tomography (PET/CT) provides fusion of both anatomical and functional information. CT-based attenuation correction replaced (68)Ge-based attenuation correction for shortening acquisition time, improving image quality and quantitative accuracy. However, due to the temporal difference of PET and CT, mis-registration and motion artifacts are observed in the attenuation-corrected images mainly due to the respiratory motion. Reducing the spatial mismatch of the PET and CT reconstructed image remains a challenge. This review provides an introduction to various respiratory image artifacts reduction techniques especially for thoracic lesions, including breathing instruction based methods, CT protocol based methods and 4-dimensional PET/CT. The advantages and drawbacks of different methods are also discussed.
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