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Updated: May 15, 2026
10:37
Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Diet and irritable bowel syndrome.
Ioan Chirila1, Florin D Petrariu, Irina Ciortescu
1University of Medicine and Pharmacy "Grigore T.Popa", Iasi, Romania. chirilaioan@yahoo.com
Journal of Gastrointestinal and Liver Diseases : JGLD
|December 21, 2012
Summary
Irritable bowel syndrome (IBS) affects 19.1% of the urban population. Specific dietary habits, including higher consumption of canned foods, processed meats, and confectionary, are associated with IBS symptoms.
Area of Science:
- Gastroenterology
- Epidemiology
- Nutritional Science
Background:
- Growing evidence links diet to Irritable Bowel Syndrome (IBS) but population-based data are scarce.
- Understanding IBS prevalence and dietary associations in diverse urban settings is crucial.
Purpose of the Study:
- To determine the prevalence of IBS in a general urban population.
- To identify specific dietary patterns associated with IBS symptoms.
Main Methods:
- A randomized sample of 300 urban adults in Romania were interviewed.
- IBS diagnosis utilized Rome III criteria; dietary habits were assessed via food frequency questionnaires.
- Logistic regression analysis identified significant associations (Odds Ratios with 95% Confidence Intervals).
Main Results:
- The study achieved a 64.3% participation rate, with 193 subjects completing the assessment.
- The prevalence of IBS was 19.1% (19.4% female, 18.7% male), increasing with age.
- IBS was significantly associated with higher intake of canned foods, processed meats, legumes, whole cereals, confectionary, fruit compotes, and herb teas.
Conclusions:
- This study provides updated prevalence data for IBS in an urban Romanian population.
- A significant association between specific dietary components and IBS symptoms was identified, highlighting potential targets for dietary interventions.
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