Related Experiment Videos
Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase
M Trus1, N Benvenisty, H Cohen
1Department of Developmental Biochemistry, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Molecular and Cellular Biology
|May 1, 1990
Abstract:
A sequential pattern of interactions of trans-acting factors in rat liver with the phosphoenolpyruvate carboxykinase promoter during late development was observed. A liver-enriched factor, possibly AF1, interacted with the promoter in fetal liver, whereas a factor with the characteristics of C/EBP bound the promoter after birth with the onset of the gene expression.