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Updated: May 15, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Using a symptom diary to investigate work-related urticaria.
1Division of Preventive Medicine, University of Alberta, Edmonton T6G 2T4, Canada. eugene.waclawski@ualberta.ca
A nurse experienced allergic reactions, including urticaria, linked to workplace allergens in an asthma clinic. A symptom diary confirmed a strong association between her symptoms and workdays, leading to symptom improvement upon removal from exposure.
Area of Science:
- Occupational health
- Allergology
- Clinical immunology
Background:
- Occupational asthma management often overlooks diary strategies.
- Diary keeping is a recommended approach for occupational asthma.
- This case highlights diary utility in chronic urticaria linked to occupational exposure.
Observation:
- A healthcare worker in a pediatric asthma clinic developed allergic reactions.
- Reactions included eyelid swelling and urticaria on various body parts.
- A symptom diary was employed to correlate reactions with work activities.
Findings:
- The patient reported urticarial symptoms, rhinitis, and wheeze predominantly on workdays (74%) versus non-workdays (28%).
- Statistical analysis revealed a significant association (P < 0.01) between symptom occurrence and workdays.
- The diary effectively captured the link between workplace allergen exposure and allergic reactions.
Implications:
- Standard medical management failed to control the patient's symptoms.
- Symptom resolution occurred after removal from the specific work environment.
- Diary recording confirmed the causal relationship between occupational exposure and allergic symptoms, aiding in diagnosis and management.
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