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Chromoblastomycosis in Malaysia.

P Jayalakshmi1, L M Looi, T S Soo-Hoo

  • 1Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur.

Mycopathologia
|January 1, 1990
PubMed
Summary

This study reports nine male chromoblastomycosis cases in Malaysia, aged 56-65, with lower limb lesions. Diagnosis confirmed by identifying characteristic brown muriform cells in tissue sections.

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Area of Science:

  • Dermatology
  • Mycology
  • Pathology

Background:

  • Chromoblastomycosis is a chronic fungal infection affecting the skin and subcutaneous tissues.
  • It is prevalent in tropical and subtropical regions worldwide.
  • Diagnosis often relies on histopathological examination.

Purpose of the Study:

  • To report and characterize cases of chromoblastomycosis diagnosed in Malaysia.
  • To highlight clinical and histopathological findings in a series of patients.

Main Methods:

  • Retrospective review of nine histologically diagnosed cases of chromoblastomycosis.
  • Analysis of patient demographics, clinical presentation, lesion location, and duration of symptoms.
  • Histopathological examination of tissue sections to identify characteristic fungal elements.

Main Results:

  • Nine male patients aged 56-65 years were diagnosed with chromoblastomycosis.
  • All lesions were located on the lower limbs.
  • Symptom duration ranged from 5 months to 13 years.
  • Clinical suspicion of malignancy was noted in 5 cases.
  • Characteristic brown muriform cells were identified in tissue sections for diagnosis.

Conclusions:

  • Chromoblastomycosis presents in middle-aged to elderly males in Malaysia, primarily affecting the lower limbs.
  • Histopathological identification of brown muriform cells is crucial for accurate diagnosis.
  • The differential diagnosis should include malignancy, given clinical presentations.

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