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Updated: May 15, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Spontaneous cerebrospinal fluid leak and management of intracranial pressure
Zachary M Soler1, Rodney J Schlosser
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.
Abstract:
Cases of cerebrospinal fluid (CSF) rhinorrhea without a clear etiology are known as spontaneous CSF leaks. Spontaneous CSF leaks most commonly occur in the ethmoid skull base or lateral sphenoid and rarely stop without surgical intervention. This chapter reviews the clinical presentation, diagnostic workup, and treatment of patients with spontaneous CSF rhinorrhea. Specific attention will be given to endoscopic methods of repair and the importance of idiopathic intracranial hypertension as a possible comorbidity and contributing factor.
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