Related Experiment Video
Updated: May 15, 2026

08:15
Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
Published on: June 26, 2020
Formation and helicity control of ssDNA templated porphyrin nanoassemblies
Gevorg Sargsyan1, Alexandra A Schatz, Jan Kubelka
1Department of Chemistry, University of Wyoming, 1000 E. University Avenue, Laramie, WY 82071, USA.
Abstract:
We report the formation of left- (M-helix) and right-handed (P-helix) nanoassemblies of a porphyrin-diaminopurine conjugate (Por-DAP) templated by a single stranded oligodeoxythymidine (dT40) via directional hydrogen bonding. The supramolecular helicity can be controlled by the ionic strength, Por-DAP : dT40 ratio, and annealing rate.

