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Related Concept Videos

Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...

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A GMP-Compliant Procedure for the Generation of Gene-Modified T cells
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[GammadeltaT cell therapy].

Yoshimasa Tanaka1, Haruki Okamura

  • 1Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 25, 2012
PubMed
Summary
This summary is machine-generated.

Human gammadeltaT cells show promise in cancer immunotherapy by targeting tumor cells. Interleukin-18 (IL-18) aids in expanding these crucial immune cells, offering new therapeutic avenues.

Area of Science:

  • Immunology
  • Cancer Research
  • Cell Biology

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