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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Screening for prostate cancer: an updated review
Gustavo Nader Marta1, Samir Abdallah Hanna, João Luis Fernandes da Silva
1Radiation Oncology Department-Hospital Sírio-Libanês, Rua Dona Adma Jafet 91, Sao Paulo-SP, Brazil. gnmarta@uol.com.br
Expert Review of Anticancer Therapy
|December 25, 2012
Summary
Prostate cancer screening using prostatic-specific antigen (PSA) improves early detection but may lead to overdiagnosis. Recent recommendations and screening methods are updated, focusing on benefits for younger men.
Area of Science:
- Oncology
- Urology
Background:
- Prostate cancer is a leading male malignancy with increasing incidence.
- Prostatic-specific antigen (PSA) discovery revolutionized prostate cancer diagnosis and treatment.
- PSA screening enhances early detection, particularly in asymptomatic men.
Purpose of the Study:
- To provide an update on prostate cancer screening methods.
- To present current recommendations for prostate cancer screening.
- To discuss the implications of screening on overdiagnosis and overtreatment.
Main Methods:
- Review of recent randomized trials on prostate cancer screening.
- Analysis of the impact of PSA screening on detection rates.
- Evaluation of benefits versus risks of prostate cancer screening.
Main Results:
- Early detection rates have significantly increased due to PSA screening.
- The benefits of screening on overall mortality rates are not definitively established.
- Younger men with longer life expectancies may gain the most from screening.
Conclusions:
- Prostate cancer screening offers benefits in early detection but raises concerns about overdiagnosis.
- Current screening strategies require careful consideration of individual patient factors.
- Updated recommendations aim to optimize screening practices for prostate cancer.
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