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Adenovirus serotype 14 infection, New Brunswick, Canada, 2011

Gabriel Girouard1, Richard Garceau, Louise Thibault

  • 1Centre hospitalier universitaire Dr-Georges-L.-Dumont, Moncton, New Brunswick, Canada. gabriel.girouard@vitalitenb.ca

Emerging Infectious Diseases
|December 25, 2012
PubMed

Insights

Three cases of adenovirus serotype 14 infection were identified in New Brunswick, Canada. These strains were linked to adenovirus 14p1, a variant found in the US and Ireland, highlighting an emerging public health concern.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Adenovirus serotype 14 (HAdV-14) is a significant human pathogen.
  • Genomic variants of HAdV-14 have emerged globally.
  • Surveillance for novel and re-emerging viral strains is crucial.

Observation:

  • Three culture-proven cases of HAdV-14 infection occurred in New Brunswick, Canada, in the summer of 2011.
  • Patients presented with severe illness.
  • Isolated viral strains were genetically similar to the HAdV-14p1 genomic variant.

Findings:

  • The HAdV-14p1 genomic variant, previously identified in the United States and Ireland, was detected in Canadian patients.
  • The circulating strains in Canada were closely related to international HAdV-14p1 isolates.
  • This indicates potential international transmission or a shared source of the variant.

Implications:

  • Physicians in Canada should be aware of the emergence of HAdV-14 and its potential for severe disease.
  • Enhanced surveillance for HAdV-14 is warranted in Canada.
  • Understanding the epidemiology of HAdV-14p1 is important for public health preparedness and response.

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