Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Pneumothorax II: Pathophysiology01:08

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trajectories of emotional and physical distress during ICU stay and their association with clinical factors and cognitive status at discharge.

Scientific reports·2026
Same author

Cognitive reserve: an emerging dimension in post-ICU recovery stratification.

Intensive care medicine·2025
Same author

Inherited SCN1A missense mutation in a Dravet Syndrome family: Neuropathological correlation, family screening and implications for adult carriers.

Epilepsy research·2023
Same author

Characterization and management of cognitive and emotional alterations in COVID-19 critically ill patients after ICU discharge.

Medicina intensiva·2022
Same author

Aggressive alveolar recruitment in ARDS: More shadows than lights.

Medicina intensiva·2021
Same author

Characterization and management of cognitive and emotional alterations in COVID-19 critically ill patients after ICU discharge.

Medicina intensiva·2021

Related Experiment Video

Updated: May 15, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

[Lung-brain interaction in the mechanically ventilated patient].

J López-Aguilar1, M S Fernández-Gonzalo, M Turon

  • 1Fundació Parc Taulí, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, España; Institut Universitari Parc Taulí, Universitat Autònoma de Barcelona, Campus d' Excelència Internacional, Bellaterra, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, España; Servicio de Medicina Intensiva, Hospital de Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, España.

Medicina Intensiva
|December 25, 2012
PubMed
Summary

Critically ill patients with acute respiratory distress syndrome (ARDS) experience significant neuropsychological changes affecting quality of life. Understanding lung-brain interactions during mechanical ventilation is crucial for improving patient outcomes.

Keywords:
Acute lung injuryAcute respiratory distress syndromeAlteraciones neuropsicológicas y cognitivasCentral nervous systemConfusional syndromeDelirioDeliriumIntensive care unitInteracción pulmón-cerebroLesión pulmonar agudaLung-brain interactionMechanical ventilationNeuropsychological and cognitive impairmentSistema nervioso centralSíndrome confusionalSíndrome de distrés respiratorio agudoUnidad de cuidados intensivosVentilación mecánica

More Related Videos

A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
05:56

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

Related Experiment Videos

Last Updated: May 15, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

A Structured Approach to Extubation in Mechanically Ventilated Rats
05:05

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
05:56

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

Area of Science:

  • Critical Care Medicine
  • Neuroscience
  • Pulmonology

Background:

  • Patients in intensive care units (ICUs) with acute lung injury or acute respiratory distress syndrome (ARDS) often exhibit neuropsychological alterations.
  • These alterations frequently persist beyond the acute illness phase, negatively impacting patients' quality of life.

Purpose of the Study:

  • To analyze the intricate relationship between lung and brain functions in mechanically ventilated critical care patients.
  • To provide an updated review of neuropsychological changes and their underlying mechanisms in this patient population.

Main Methods:

  • Literature review focusing on neuropsychological alterations in ICU patients.
  • Analysis of lung-brain interactions during mechanical ventilation.
  • Exploration of the etiology and mechanisms of neurological disorders in critical illness.

Main Results:

  • Neuropsychological deficits are common during ICU stay and at discharge for patients with ARDS.
  • Mechanical ventilation influences lung-brain interactions, contributing to neurological complications.
  • Various factors contribute to the development of neurological disorders in critically ill patients.

Conclusions:

  • A comprehensive management approach is essential for critical care patients to mitigate short-, middle-, and long-term adverse effects.
  • Addressing lung-brain interactions is key to managing neurological sequelae in ARDS patients.
  • Further research into the mechanisms of neurological dysfunction can inform therapeutic strategies.