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Updated: May 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Staphylococcus aureus causing tropical pyomyositis, Amazon Basin, Peru.

Coralith García¹, Marie Hallin, Ariane Deplano

¹Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru. coralith.garcia@upch.pe

Emerging Infectious Diseases

|December 25, 2012

Summary

This study identified Staphylococcus aureus strains causing tropical pyomyositis in Peru. Sequence type 25 strains carrying Panton-Valentine leukocidin genes are circulating in South America.

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Last Updated: May 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Area of Science:

Microbiology
Infectious Diseases
Tropical Medicine

Background:

Tropical pyomyositis is a bacterial infection primarily affecting skeletal muscles.
Staphylococcus aureus is a common pathogen, but its prevalence in tropical pyomyositis in the Amazon Basin is less understood.
Understanding the genetic characteristics of S. aureus strains is crucial for effective treatment and public health strategies.

Purpose of the Study:

To characterize Staphylococcus aureus isolates from patients with tropical pyomyositis in the Peruvian Amazon.
To identify specific genetic markers, such as Panton-Valentine leukocidin genes and multilocus sequence types, within these isolates.
To determine the potential circulation of specific S. aureus sequence types in this tropical region.

Main Methods:

Collection and microbiological analysis of 12 Staphylococcus aureus isolates from patients with tropical pyomyositis.
Methicillin susceptibility testing.
Detection of Panton-Valentine leukocidin-encoding genes using molecular methods.
Multilocus sequence typing (MLST) to determine the genetic lineage of the isolates.
Analysis for the presence of enterotoxin genes.

Main Results:

All 12 Staphylococcus aureus isolates were susceptible to methicillin.
Eleven out of 12 isolates (91.7%) harbored Panton-Valentine leukocidin-encoding genes.
Five isolates (41.7%) belonged to multilocus sequence type 25 (ST25).
These ST25 isolates also possessed a wide array of enterotoxin genes.
No methicillin-resistant Staphylococcus aureus (MRSA) was detected.

Conclusions:

Methicillin-susceptible Staphylococcus aureus (MSSA) strains are implicated in tropical pyomyositis in the Peruvian Amazon.
The high prevalence of Panton-Valentine leukocidin genes in these MSSA isolates is noteworthy.
The findings strongly suggest that multilocus sequence type 25 is a significant and circulating lineage in tropical South America, associated with pyomyositis and carrying virulence factors.