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Inherited heart rhythm disease: negotiating the minefield for the practicing cardiologist

Andrew D Krahn1, Shubhayan Sanatani, Martin J Gardner

  • 1Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada. akrahn@mail.ubc.ca

The Canadian Journal of Cardiology
|December 25, 2012
PubMed

Insights

Inherited heart rhythm disorders, including channelopathies and cardiomyopathies, pose diagnostic and management challenges. This review offers guidance for clinicians and highlights resources for improved patient care and family screening.

Area of Science:

  • Cardiology
  • Genetics
  • Clinical Medicine

Background:

  • Inherited heart rhythm disorders are uncommon yet challenging for clinicians.
  • Key electrical disorders include long QT syndrome, Brugada syndrome, and catecholaminergic ventricular tachycardia.
  • Inherited cardiomyopathies like hypertrophic and arrhythmogenic right ventricular cardiomyopathy also cause arrhythmias and sudden death.

Purpose of the Study:

  • To review diagnostic considerations for inherited heart rhythm disorders.
  • To provide guidance for the day-to-day management of these conditions.
  • To highlight accessible resources for healthcare professionals and patients.

Main Methods:

  • Review of key historic and diagnostic considerations.
  • Discussion of management strategies and accessible resources.
  • Emphasis on disease-specific treatments and family screening.

Main Results:

  • Inherited heart rhythm disorders present diagnostic and management difficulties.
  • Accessible resources and expert clinics can aid healthcare providers.
  • Common measures can assist providers and reduce patient risk.

Conclusions:

  • Effective management of inherited heart rhythm disorders requires careful diagnosis and tailored treatment.
  • Utilizing expert networks and available resources improves patient outcomes.
  • Family screening is crucial for identifying at-risk individuals.

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