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Published on: February 23, 2014
Cost of hospitalizing children with invasive pneumococcal pneumonia
Pedro Brotons1, Gemma Gelabert, Cristian Launes
1Department of Microbiology, Hospital Sant Joan de Déu-University of Barcelona, Esplugues, Barcelona, Spain.
Insights
Invasive pneumococcal pneumonia in children incurs significant hospital costs, averaging over €4500 per case. Complications, surgery, and intensive care dramatically increase these expenses, highlighting the need for preventative immunization.
Area of Science:
- Pediatric Infectious Diseases
- Health Economics
- Public Health
Background:
- Invasive pneumococcal pneumonia (IPP) is a major cause of childhood hospitalization.
- Limited data exists on the economic burden and resource utilization of IPP in pediatric populations.
Purpose of the Study:
- To determine the hospital costs associated with pediatric IPP.
- To identify key factors influencing the cost of IPP hospitalizations.
Main Methods:
- Observational economic evaluation of 135 children (<18 years) with culture-proven IPP.
- Data collected from January 2001 to December 2011 in Barcelona, Spain.
- Analysis included demographic, clinical, microbiological, and epidemiological variables.
Main Results:
- Median hospital cost for IPP was €4533 (95% CI: €4078-€5435) with a median stay of 11 days.
- Complicated pneumonia, surgery, intensive care, and non-PCV7 serotypes were significant cost drivers.
- Costs for complicated pneumonia ranged from €2822 to €4919, compared to €1399 for non-complicated cases.
Conclusions:
- Pediatric IPP places a substantial burden on healthcare resources.
- Universal childhood immunization programs with PCV13 and prompt complication management can reduce costs.
- Targeted interventions are crucial for mitigating the financial impact of IPP.
Background:
Although invasive pneumococcal pneumonia remains responsible for a significant number of child hospitalizations, specific data on hospital resource utilization and related costs are limited.
Objectives:
To assess the cost of hospitalizing children with invasive pneumococcal pneumonia and identify the cost determinants of the disease.
Patients And Methods:
Economic evaluation based on an observational study of all children <18 years of age with culture-proved invasive pneumococcal pneumonia admitted to a referral hospital in Barcelona (Spain) during the period January 2001-December 2011. Analysis included demographic, microbiological, epidemiological and clinical variables.
Results:
A total of 135 children were included in the study (median age 3.3 years). PCV13 serotypes were detected in 132 (97.8%) cases. Median hospital cost was €4533 (€4078-5435, 95% CI). Median length of stay was 11.0 days (10.6-13.0 days, 95% CI). Variables significantly associated with increased cost in the multivariate analysis were complicated pneumonia (≥2 and 1 complication) versus non-complicated pneumonia (€4919 and €2822 vs. €1399), performance of surgery versus no surgery (€4849 vs. €1435), intensive care versus no intensive care (€6488 vs. €3862) and identification of non-PCV7 serotypes versus PCV7 serotypes (€4656 vs. €1470).
Conclusion:
Invasive pneumococcal pneumonia in children makes substantial demands on hospital health care and financial resources that could be mitigated with universal PCV13 childhood immunization programmes and early management of complications.
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