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Updated: May 15, 2026
06:41
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Extracorporeal membrane oxygenation as an alternative to ventilation
Ignacio Malagon1, Donna Greenhalgh
1Department of Cardiothoracic Anaesthesia, University Hospital of South Manchester, Manchester, UK. ignaciomalagon@hotmail.com
Current Opinion in Anaesthesiology
|December 25, 2012
Summary
Extracorporeal membrane oxygenation (ECMO) offers superior lung rest compared to conventional ventilation for acute respiratory failure. Further research is needed to optimize its use and potentially establish ECMO as a first-line treatment.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Cardiopulmonary Support
Background:
- Renewed interest in extracorporeal membrane oxygenation (ECMO) for acute respiratory failure post-H1N1 epidemic.
- Technological advancements now recommend ECMO as a definitive treatment.
- Limited randomized trials and cohort studies exist for ECMO therapy.
Purpose of the Study:
- To review current indications and uses of ECMO in acute respiratory failure.
- To discuss the expanding applications of ECMO.
- To highlight areas for future research in ECMO therapy.
Main Methods:
- Review of current literature on ECMO for acute respiratory failure.
- Analysis of expanded indications for ECMO.
- Discussion of potential future research directions.
Main Results:
- ECMO demonstrates superiority over conventional ventilation in providing lung rest.
- Expanded indications include bridge to lung transplantation, awake ECMO, liver transplantation, and ARDS.
- Current results support the efficacy of ECMO in various critical care scenarios.
Conclusions:
- Further studies are essential to validate and define ECMO's role.
- Pharmacodynamic and pharmacokinetic studies are warranted.
- Reducing intracerebral hemorrhage incidence could position ECMO as a first-line treatment for acute respiratory failure.
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