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Related Experiment Video

Updated: May 15, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo

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Two-reference swept-source optical coherence tomography of high operation flexibility.

Ting-Ta Chi¹, Chiung-Ting Wu, Chen-Chin Liao

¹Institute of Photonics and Optoelectronics, National Taiwan University, 1, Roosevelt Road, Section 4, Taipei, 10617 Taiwan.

|December 25, 2012

Summary

A new spatially localized image processing method allows for less stringent operation of two-reference swept-source optical coherence tomography (OCT) systems. This technique effectively suppresses mirror images with a phase difference greater than 20 degrees, enhancing flexibility.

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Area of Science:

Biomedical Optics
Medical Imaging Technology
Optical Engineering

Background:

Swept-source optical coherence tomography (OCT) is a crucial imaging modality.
Mirror image artifacts degrade OCT image quality and limit diagnostic capabilities.
Traditional methods for mirror image suppression require precise phase control.

Purpose of the Study:

To demonstrate a less stringent operational method for two-reference OCT systems.
To suppress mirror images using a spatially localized image processing technique.
To enable full-range optical Doppler tomography.

Main Methods:

Implementation of a two-reference swept-source OCT system.
Application of a spatially localized image processing method for mirror image suppression.
Phantom experiments to validate the technique and its integration with optical Doppler tomography.

Main Results:

Effective mirror image suppression achieved with a phase difference greater than 20 degrees, significantly relaxing operational constraints.
Demonstrated increased flexibility in adjusting beam splitter orientation.
Successful implementation of full-range optical Doppler tomography by combining the mirror image suppression method with two-reference OCT.

Conclusions:

The spatially localized image processing method offers a more flexible and less stringent approach to mirror image suppression in two-reference OCT.
This advancement facilitates the practical application of full-range optical Doppler tomography.
The findings have implications for improving OCT-based diagnostic imaging.