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Genetically epileptic rats show a pronounced intermediate stage of sleep
G Gandolfo1, S Romettino, C Gottesmann
1Laboratoire de Psychophysiologie, Faculté des Sciences et Techniques, Nice, France.
Physiology & Behavior
|January 1, 1990
Abstract:
Rats of the genetically epileptic WAG/Rij strain show a more long-lasting intermediate stage of sleep compared to rats of the Wistar strain. Therefore the WAG/Rij strain provides a privileged model for studying this stage of sleep. On the other hand, the percentage of paradoxical sleep in WAG/Rij rats is lower than in Wistar rats, for the reason that the intermediate stage in WAG/Rij rats is less frequently followed by paradoxical sleep and more frequently by slow wave sleep and especially by arousals. It is speculated that the epileptic rats encounter a greater difficulty in entering into paradoxical sleep.