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Cost-effectiveness of secondary screening modalities for hypertension
Y Claire Wang1, Alisa M Koval, Miyabi Nakamura
1Department of Health Policy and Management, Columbia Mailman School of Public Health, Stony Brook University, New York, NY, USA. ycw2102@columbia.edu
Insights
Home blood pressure monitoring (HBPM) and ambulatory blood pressure monitoring (ABPM) are cost-effective additions to clinic-based blood pressure (CBP) screening for hypertension diagnosis. These methods improve accuracy and aid treatment decisions.
Area of Science:
- Cardiovascular Medicine
- Health Economics
Background:
- Clinic-based blood pressure (CBP) diagnosis of hypertension can lead to misclassification (masked or white-coat hypertension).
- Home blood pressure monitoring (HBPM) and ambulatory blood pressure monitoring (ABPM) offer improved diagnostic accuracy.
Purpose of the Study:
- To review the literature on the costs and cost-effectiveness of incorporating HBPM and ABPM into routine blood pressure screening.
Main Methods:
- Systematic literature review of cost and cost-effectiveness studies.
- Included studies compared two or more blood pressure monitoring modalities in adults.
- Excluded were letters, editorials, and studies on specific populations (pregnant, children, diabetes).
Main Results:
- Fourteen studies were included, analyzing cost outcomes.
- Ambulatory blood pressure monitoring (ABPM) was cost-saving for diagnostic confirmation after elevated CBP in six studies.
- Adding home blood pressure monitoring (HBPM) to elevated CBP was cost-effective in three of four studies.
Conclusions:
- Evidence supports the cost-effectiveness of using HBPM or ABPM after initial CBP diagnosis.
- Further research should explore implementation, long-term economic value, and utility in identifying masked hypertension.
Background:
Clinic-based blood pressure (CBP) has been the default approach for the diagnosis of hypertension, but patients may be misclassified because of masked hypertension (false negative) or 'white coat' hypertension (false positive). The incorporation of other diagnostic modalities, such as home blood pressure monitoring (HBPM) and ambulatory blood pressure monitoring (ABPM), holds promise to improve diagnostic accuracy and subsequent treatment decisions.
Materials And Methods:
We reviewed the literature on the costs and cost-effectiveness of adding HBPM and ABPM to routine blood pressure screening in adults. We excluded letters, editorials, and studies of pregnant and/or pre-eclamptic patients, children, and patients with specific conditions (e.g. diabetes).
Results:
We identified 14 original, English language studies that included cost outcomes and compared two or more modalities. ABPM was found to be cost saving for diagnostic confirmation following an elevated CBP in six studies. Three of four studies found that adding HBPM to an elevated CBP was also cost-effective.
Conclusion:
Existing evidence supports the cost-effectiveness of incorporating HBPM or ABPM after an initial CBP-based diagnosis of hypertension. Future research should focus on their implementation in clinical practice, long-term economic values, and potential roles in identifying masked hypertension.
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