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Related Concept Videos

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Correlation between ECG and Cardiac Cycle

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Related Experiment Video

Updated: May 15, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Echocardiographic changes after cardiac resynchronisation therapy.

Rudolf Praus1, Ludek Haman, Miloslav Tauchman

  • 1Department of Cardiovascular Medicine, University Hospital, Hradec Kralove, Czech Republic. rudolfpraus@seznam.cz

Kardiologia Polska
|December 25, 2012
PubMed
Summary

Cardiac resynchronisation therapy (CRT) significantly improved echocardiographic parameters in responders within 3 months, with further right ventricular improvements seen at 15 months. Nonresponders showed limited improvement and worsening tricuspid regurgitation.

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Last Updated: May 15, 2026

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Published on: July 12, 2022

Area of Science:

  • Cardiology
  • Medical Imaging
  • Heart Failure Management

Background:

  • Cardiac resynchronisation therapy (CRT) is used to treat heart failure.
  • Understanding echocardiographic changes post-CRT is crucial for assessing treatment efficacy.
  • Differentiating responders from nonresponders can guide clinical management.

Purpose of the Study:

  • To evaluate echocardiographic changes in patients undergoing CRT.
  • To compare changes between clinical responders and nonresponders at 3 and 15 months.
  • To identify predictors of CRT response.

Main Methods:

  • Prospective study of 58 patients receiving biventricular CRT.
  • Echocardiographic and clinical parameters assessed at baseline, 3, and 15 months.
  • Clinical responders defined by improvements in quality of life, NYHA class, and 6-minute walk test.

Main Results:

  • Responders showed significant improvements in LV dimensions, ejection fraction, and pressures by 3 months.
  • Right ventricular function and size improved significantly in responders only by 15 months.
  • Nonresponders had minimal improvements, with worsening tricuspid regurgitation observed at 15 months.

Conclusions:

  • Most echocardiographic improvements in CRT responders occur within 3 months.
  • Sustained RV improvements are observed later, at 15 months, in responders.
  • Baseline interventricular dyssynchrony and creatinine predict CRT response.