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[Sustained ventricular tachycardia: inducibility during invasive electrophysiologic studies]
J Schlaepfer1, M Fromer, J J Goy
1Département de médecine interne, CHUV, Lausanne.
Schweizerische Medizinische Wochenschrift
|March 31, 1990
Summary
Electrophysiologic studies effectively induce sustained ventricular tachycardia in most patients with heart disease. However, this diagnostic method is less sensitive in individuals without underlying cardiac conditions.
Area of Science:
- Cardiology
- Electrophysiology
Context:
- Sustained ventricular tachycardia (VT) diagnosis and treatment rely on electrophysiologic studies (EPS).
- Successful EPS requires demonstrating high inducibility of spontaneous VT.
- The study prospectively evaluated VT induction yield in 35 patients with documented VT history.
Purpose:
- To determine the induction yield of sustained ventricular tachycardia using electrophysiologic studies.
- To assess the utility of EPS for electropharmacologic testing in various patient groups.
Summary:
- Electrophysiologic studies successfully induced sustained VT in 100% of patients with coronary artery disease and cardiomyopathy.
- Induction rates were 75% for other organic heart diseases and 33% for patients without detectable heart disease.
- The protocol involved programmed electrical stimulation and isoproterenol administration.
Impact:
- Electrophysiologic studies demonstrate a high yield for VT induction in patients with organic heart disease, supporting electropharmacologic testing.
- Low sensitivity in patients without heart disease limits the use of EPS for drug efficacy testing in this population.