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Related Experiment Video

Updated: May 15, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Total arch replacement using antegrade cerebral perfusion.

Yutaka Okita1, Kenji Okada, Atsushi Omura

  • 1Division of Cardiovascular Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. yokita@med.kobe-u.ac.jp

The Journal of Thoracic and Cardiovascular Surgery
|December 26, 2012
PubMed
Summary
This summary is machine-generated.

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Total aortic arch replacement using antegrade cerebral perfusion demonstrates low hospital mortality and morbidity. This surgical technique offers favorable long-term survival rates for patients with complex aortic conditions.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Vascular Surgery

Background:

  • Aortic arch replacement is a complex procedure with significant risks.
  • Antegrade cerebral perfusion (ACP) is a technique used to protect the brain during aortic arch surgery.
  • Optimizing surgical techniques is crucial for improving patient outcomes.

Purpose of the Study:

  • To present the technical details of total aortic arch replacement using antegrade cerebral perfusion.
  • To evaluate the safety and efficacy of this approach in a large patient cohort.
  • To identify risk factors for hospital mortality and assess long-term outcomes.

Main Methods:

  • A retrospective review of 423 consecutive patients undergoing total aortic arch replacement with ACP from 2002 to 2012.

Related Experiment Videos

Last Updated: May 15, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

  • Detailed description of surgical technique including cannulation, ACP management, temperature control, and graft selection.
  • Analysis of perioperative outcomes, hospital mortality, permanent neurologic deficits, and long-term survival.

    • Main Results:

    • Overall hospital mortality was 4.5%, with lower rates in elective cases (2.1%) compared to urgent/emergency cases (9.6%).
    • Permanent neurologic deficits occurred in 3.3% of patients.
    • Five- and 10-year survival rates were 79.6% and 71.2%, respectively, with excellent outcomes in acute aortic dissection patients.

    Conclusions:

    • The presented approach for total aortic arch replacement with antegrade cerebral perfusion is associated with low hospital mortality and morbidity.
    • This technique leads to favorable long-term outcomes and survival.
    • Meticulous surgical technique and patient selection are key to successful aortic arch repair.