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Controlled Strain of 3D Hydrogels under Live Microscopy Imaging
Published on: December 4, 2020
The future of silicone hydrogels.
Padmaja Sankaridurg1, Percy Lazon de la Jara, Brien Holden
1Brien Holden Vision Institute, Sydney, Australia. p.sankaridurg@brienholdenvision.org
Eye & Contact Lens
|December 26, 2012
Summary
Silicone hydrogel contact lenses dominate due to reduced hypoxia effects, but dryness and adverse events remain challenges. Opportunities exist for myopia control and correcting refractive errors.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Optometry
Background:
- Silicone hydrogel contact lenses represent a significant advancement in lens technology.
- Their high oxygen permeability has reduced hypoxia-related issues like limbal redness, making them the preferred choice for new wearers.
Purpose of the Study:
- To review the current state of silicone hydrogel contact lens technology.
- To discuss the challenges and opportunities associated with their use, including wearer comfort, adverse events, and new applications.
Main Methods:
- Literature review of recent advancements in silicone hydrogel contact lens materials and designs.
- Analysis of clinical data regarding lens performance, wearer satisfaction, and adverse event rates.
- Exploration of emerging applications for silicone hydrogel lenses.
Main Results:
- Silicone hydrogel lenses have largely mitigated hypoxia-induced complications but end-of-day dryness and discomfort persist.
- Serious adverse events like microbial keratitis have not decreased, and issues with lens care product compatibility cause corneal staining and infiltrates.
- The high oxygen transmissibility platform enables expansion into astigmatism, presbyopia, and myopia control contact lenses.
Conclusions:
- Despite advancements, challenges in comfort and adverse event profiles require further attention.
- The unique properties of silicone hydrogel lenses offer significant opportunities for expanding contact lens applications, particularly in myopia management and vision correction for complex refractive errors.
